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Therapeutic compounds and clinical products are actual remedies that can be used to treat diseases. Oxis has several therapeutic compounds that are available to be licensed including anti-inflammatory and several therapeutic antioxidant mimics with potential applications in the treatment of neurodegenerative (Alzheimer’s and Parkinson’s), cardiovascular diseases, diabetes and other conditions.

OXIS’ goal is to control both direct cellular abnormalities and damage from ROS and RNS. One of ways that this can be accomplished is by using OXIS’s compounds to modulate the activation of certain molecules called transcription factors. Transcription factors are the central control switches in the body that can trigger and modulate a cascade of interrelated events. Activation of transcription factors by ROS/RNS can accelerate inflammatory responses that can cause and contribute to cell death in degenerative and other diseases. OXIS is in the process of early stage development of therapeutic molecules that have the ability to counteract some of these unwanted responses and perhaps be able to counteract different health abnormalities.

Check out: http://www.oxis.com

For how wonderful is the life in your hands
Give it a meaning before it is in the stands

You may just think the best is a horizon out of reach
Ponder not and waste a moment into the search

Endure the best in you to make the future astound
Let the zeal in your heart color the world around

Past is a lesson and Present is a liaison
Every new day is a step to the destination

Make each moment the best in your scope
For, its always the beginning of a new hope

Wishing you a Relishing and Blissful New Year Ahead

-By Vijay Kunchakuri

You made a plan to lose weight, but what can you do in the mean time? You can dress 10 pounds thinner. Here are a few tips so you can dress 10 pounds thinner.

• A-Line Skirt - Try a simple A-line cut in a stretch blend, a wide waistband holds in the stomach, while the A shape creates a smooth line to disguise full thighs.

• Get thin quick tip - Slip on high heels that match your skin tone, which will make you look longer and leaner because there’s no contrasting color to break up the leg line.

• Wear one solid color from head to toe. Preferably, dark colors like black or navy. This will lengthen your body making you appear leaner and taller.

• Super wide belts are wonderful. Wide belts will help cinch you in and create a spectacular hourglass shape. Choose a fun bright color that puts a break in your outfit. For instance, if you choose an all black outfit, choose a bright pink or bright yellow belt to wear around your waist.

• Choose a slimming neckline pick a top that draws attention UP. V-neck’s will draw people’s attention to your face and away from what you may consider trouble areas. So, for example, pick a V-neck and flared leg trouser pants to generate the idea that you have longer legs and a smaller waist.

• If you choose to wear a dress pick one that is knee length and an empire waistline. Empire waistlines move smoothly over your stomach and fits closely at the smallest part of the upper body. These types of dresses tend to look flattering on almost everyone.

Here are few tips on setting things right, once you have indulged to your heart’s content.

CHEESY PIZZA

After a cheesy pizza, your next meal should be a plain bowl of steamed vegetables to compensate for the fiber. You can couple it with some brown rice or multigrain bread.

CHOCOLATE CAKE

After having a chocolate cake you may actually suffer with constipation and the best meal to beat that constipation caused by a chocolate cake is a bowl of piping hot vegetable stew teamed with whole grain bread or barley soup.

AERATED DRINKS

Beat the acidity by drinking gallons of water throughout the day. You can also have a tall glass of butter milk, cold milk, coconut water or apple juice.

ICE-CREAM

Most of the ice creams have artificial color and preservatives that meddle with the digestive juices, making it difficult to process. Gulp down a glass of butter milk. Your next meal should be a bowl of spinach soup with a slice of rye bread which will ensure smooth bowel movements.

SPICY FOODS

Eating spicy foods can lead to stomach distension and acidity. A plain glass of cold milk will help fight that acidity. Your next meal should be a bowl of sprouts salad. These foods contain Vitamin B and Vitamin E that help eliminate acids out of the body.

CHINESE FOOD

Most of Chinese meals are cooked with a generous sprinkling of ajinomoto whose hazards are well known. Water and green tea is the best way to detox our body. Balance the excessive salt intake by consuming a glass of coconut water. Make sure to end your day with a bowl of mix fruits. Fruits such as papaya, peach, musk melon and pear too as these help ward off severe acidity.

Fatigue is a common health complaint. It is however, one of the hardest terms to define and a symptom of many different conditions. Fatigue is another word for extreme exhaustion of both mental and physical strength.

Weariness, tiredness, exhaustion or lethargy is generally defined as a feeling of lack of energy. Fatigue is not the same as drowsiness, but the desire to sleep may accompany fatigue. In general, drowsiness is feeling the need to sleep, while fatigue is a lack of energy and motivation. Drowsiness and apathy can be symptoms of fatigue.

Fatigue can be a normal and important response to physical exertion, emotional stress, boredom or lack of sleep. You feel you can’t go on or even talk to anyone, short breaks don’t help and you need to take a longer break to relax. Mental fatigue is caused by any prolonged activity along with high level of stress and emotions. It’s seen among individuals who work on tight dead lines for long duration and carry out tasks that require continuous attention and effort.

One can prevent fatigue by defining limits and sticking to them. Physical and mental threshold of work should be for eight hours and include some music, walk or reading in your routine then fatigue will rarely set in.

For sure-fire cures do this once a week:

Get a massage and listen to soothing music.

Eat light and go for brisk walk to pump up blood circulation.

Avoid phone calls.

Cut open, peel or deeply smell citrus fruits such as lemon, orange or lime between tasks.

Dab eucalyptus oil on a handkerchief or crush leaves by hand and inhale.

Keep a bunch of flowers like jasmine near your work space.

Can you really grow younger as you “age”? We can never think that muscles can literally turn back the genetic clock. But yes it’s true and is possible when you regularly exercise with resistance.

Resistance exercise can be weight training or just using your body weight. You can exercise that is heavy enough to cause some strain but not so heavy that it is painful or dangerous.

Some of the biology aspects of our body are really unbelievable.

The mitochondria is the energy factory of the human cell. As we age our muscles begin to show what researchers call “mitochondrial dysfunction”. This is what causes all the bad stuff associated with “sarcopenia”. Sarcopenia is just the wasting away of muscle due to age and under-use. As we age most of us will experience a gradual loss of muscle. Here comes the main problem, as muscle is active tissue it is responsible for most of the calories we use during the day.

The less muscle you have, the more body fat you will gain if you eat the same amount of food. Muscle loss is also related to the onset of many bone diseases. The muscle that holds our spine in alignment can deteriorate as we age and cause major back problems. The same is true for the muscle and tendons around the knee and hip joints.

Resistance training obviously builds muscle and it does so at any age. After just six months of resistance training strength increases by over 20%, reversal of most of the genes gets started, genes literally “revert back” to the same markers as “younger” genes and affects age in muscle tissue.

It is one thing to maintain muscle as we age while to gain muscle is even better. That is downright amazing isn’t it? Strength is not a luxury as we age. It is absolutely necessary for longevity and health. And this all takes place at the genetic level. You’ll look better and feel better than you ever have to boot.

So many people turn to plastic surgery and drugs for this same effect. There is nothing wrong with that but wouldn’t you rather use a natural and safe alternative the one that helps you in a hundred other ways? It certainly makes a body look and feel younger than any thing else can. It is a gift that can add years to your life and take away years from your looks all at the same time.

In today’s fast paced life the modern busy woman even when pregnant has no option but to travel and there is hardly any time for taking break. Many women are working even when they are in an advance stage of their pregnancy and that involves travel too. Many don’t like the idea of being home bound.

Its not that traveling is not safe for pregnant women but you just need to remember few things that will help you to make your travel comfortable and safe.

Don’t just sit:

You may be traveling by airplane or by road it is important that you get up and move around every other hour. This is more important if you are in advance stage of pregnancy as this will prevent any soreness and stiffness.

Carry snacks:

It is a good idea to have snacks in long journey. It is also safe to carry snacks with you as there might be need of eating if you get stuck in traffic or your flight is delayed and you have to wait. This will also help you to deal with usual discomforts like feeling faint which is related to blood sugar levels.

Have enough fluids:

While you travel you tend to get dehydrated and pregnant woman need lots of fluids. You can carry a water bottle or juice with you.

Dress right:

Dress in a manner that you are comfortable during a trip. You can carry a light shawl as sometimes air conditioner around you can make you feel cold.

Be prepared for emergency:

You should carry your prenatal medical records with you. You may not face any problem but there is no harm in taking them along with you as it is safe.

After leaving mainland Asia, the path crossed Japan’s Ryukyu Islands and curved southeast through the Pacific Ocean where the maximum duration of totality reached to 6 min 39 sec the Sun’s altitude was 86° and the path width was 258 km.